Where'd You Go, Bernadette: A Novel by Maria Semple
I really enjoyed this book but the main character, Bernadette, is as quirky as it gets.
Bernadette has made herself into a strange recluse. She might have been a bit off-beat in the past but now she's fodder for the gossips at her daughter's charter school in Seattle. Her husband is so wrapped up in work he hasn't really noticed. Her daughter notices but doesn't really care and has crafted her life around the oddities of her mother.
I'm afraid if I say any more it will just be a giant spoiler so that's all I'm going to say except: FBI, Antartica, Microsoft, and email. Enjoy!